Simple chemistry generates novel compounds! #memo #paper #chemoinformatics

If you are chemist, amide formation seems one of easy reaction. It’s really simple, can the reaction make novel compounds? Recently I found very interesting article in ChemRxiv written by researchers of AZ. ‘Can “easy” chemistry produce complex, diverse and novel molecules?’https://chemrxiv.org/articles/Can_Easy_Chemistry_Produce_Complex_Diverse_and_Novel_Molecules_/12563231 The author used in-house ELN dataset for analysis, compare compounds which were made