Bio-isoster of Aryl amine #memo

As medicinal chemists know that aryl amine building blocks are often used in drug design. N linked Bi Aryl motif can found many kinase inhibitors but sometime aryl amine cause toxic issues so the structure is recognized as alert structure. So, there are many researches for aryl amine replacement with another structure. Here is aContinue reading “Bio-isoster of Aryl amine #memo”