Twist and to be square #MedicinalChemistry #memo

MedChem often care about lipophilicity of their own molecule. But it is very important to keep molecular drug like profiles. Spiro cyclic building block and oxetanes are very attractive components for drug discovery. Following articles are interesting for me. The first one is letter about azaspiroheptanes and the second one is about oxetane containing molecules.Continue reading “Twist and to be square #MedicinalChemistry #memo”