The last piece of gem-difluorocycloalkans #medchem #memo #journal

Recently fluorination is one of an important strategy in medicinal chemistry, it sometime improves not only potency but also any ADMET profiles. Yes I like fluorination strategy ;) However fluorination reaction is needed very harsh conditions. So I think fluorinated building blocks are very useful for medicinal chemistry to avoid such as harsh reaction stepsContinue reading “The last piece of gem-difluorocycloalkans #medchem #memo #journal”

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