Dalia Goldman provided very cool presentation in RDKit UGM 2018 about Knime.
BTW, I need to learn knime for data preparation in this week. So I learned about knime and how to make interactive plot with knime.
At frist load SDF and calculate descriptors and fingerprint with RDKit node and the split fingerprint with FingerprintExnpander. Then conduct PCA with calculated FP.
Then convert molecule to SVG with openbabel node for visualization.
Now ready. Then run the work flow! I can view selected compounds from chemical space.
Image is below.
New version of Knime is powerful tool for not only data analysis but also data visualization. ;-)