Dark Chemical Matter (DCM) in screening deck

I was interested in the article, because of the title. “The performance of dark chemical matter in high throughput screening” https://www.ncbi.nlm.nih.gov/pubmed/27762554 What is dark chemical matter(DCM) ? The definition of DCM is that compounds, which have been tested and found inactive in 50 or more assays, exhibit hit rates that are comparable to those ofContinue reading “Dark Chemical Matter (DCM) in screening deck”