review for kinetics

I found nice review about kinetics of drug binding and residence time. http://www.ncbi.nlm.nih.gov/pubmed/25782745 To improve in vitro, in vivo potency, I some time try to get SKR for designing molecule. If I got correlation only residence time and lipophilicity or molecular weight, the information is not so good. Because too liphophilic or heavy molecule isContinue reading “review for kinetics”

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